Recently, new progress has been made in high resolution imaging system using adaptive optics for vivo human eye retina in the Institute of Optics and Electronics. High resolution (micron magnitude) dynamic imaging has been achieved for fundus retina, and the video output of the image has reached 20 frame/sec. We can make continuous dynamic tomography imaging on fundus retinal capillaries and visual cell, in the level of visual cell. This is the milestone of high resolution imaging system for vivo human retinal adaptive optics from static to dynamic.

On the basis of former high resolution static imaging technology using adaptive optics in vivo human retina, our advanced biomedical optics research team developed high-resolution dynamic imaging technology and taking the acquired tomography image as reference, we could position quickly and accurately a fine fundus image capillary layer and cell layer using dynamic technology, which improved the imaging efficiency and success rate in cell class vivo human retina.

In 1997, research on high-resolution imaging technology in vivo human eye retina adaptive optics was carried out in the Institute of Optics and Electronics. A successful breakthrough in technology has been made, including micro-deformable mirror technology, Human eye wave front detection. In 2000, based on integration deformable mirror, the first set of adaptive optics system was established, and high-resolution retinal fundus images are achieved only after the United States. With the support of Chinese Academy of Sciences, the first set of vivo human retinal imaging system using adaptive optics is developed for medical application in the world and the resolution of system is close to human eye diffraction limitation (2.6μm).

The status and changes of vivo human retinal cells have clinical diagnostic value, so it is very important to see the high-resolution image to look for more advanced, earlier diagnosis means.

Breakthrough in vivo human eye high-resolution dynamic imaging technology will supply powerful scientific tool and new detection methods for research on fundus vascular dynamics, visual physiological research and so on.

At present, clinical trials for adaptive optics retinal imager is being done, and great efforts is being made to put the vivo human eye high-resolution dynamic imaging into clinical testing as soon as possible.